Biomolecular Engineering and Bioinformatics (BMEB)


The graduate research track in Biomolecular Engineering and Bioinformatics (BMEB) accepts students from molecular biology, biochemistry, computer science, and mathematical backgrounds, and trains them in innovative, multidisciplinary bioinformatics research. The track builds upon UCSC's renowned bioinformatics program, with particular strengths in comparative and functional genomics, non-coding RNA discovery, protein bioinformatics, and structure prediction. Nineteen faculty members from four departments participate in the BMEB research track. Their research groups are internationally recognized for pioneering work on applications of Bayesian statistical methods and hidden Markov models to biological sequence data, the development of widely used computational tools for the analysis and comparison of whole genomes, protein structure and function prediction, and the discovery of non-coding RNA genes. UCSC is the primary release site for the public version of the human genome, the ENCODE project, and a focal point for archaeal and extremophile genomics.  UCSC is also a major player in protein-structure and function prediction, DNA microarray analysis, high-throughput and single-molecule sequencing, and integrative investigations of infectious disease and stem cell processes. New BMEB students undertake rigorous core coursework, conduct laboratory rotations, and are exposed to a rich environment of regular seminars and group meetings. Students interact closely with BMEB faculty members while undertaking their dissertation research, and have first-hand access to state-of-the-art computation tools and lab facilities throughout their training, including cluster computing, DNA microarray fabrication equipment, and high-throughput sequencing facilities. Students receive financial support throughout their graduate career, contingent upon remaining in good academic standing.

UCSC's graduate Program in Biomedical Sciences and Engineering is supported by training grants from the National Institute of General Medical Science and the National Human Genome Research Institute.